Enfamil® Infant

Milk-based Infant formula for infants 0-12 months.

Last Updated: Monday, January 8, 2018 - 19:00

Latest Pediatric Nutrition Study

Description/Indication

Enfamil Infant is a 20 Cal/fl oz milk-based, iron-fortified, routine formula for full-term infants 0-12 months. Enfamil Infant is clinically demonstrated to foster cognitive development through 5 years of age1. Enfamil Infant is patterned after mature breast milk* and offers proven clinical outcomes in 3 key areas: brain development, immune health and growth.

Product Features:

  • DHA at the clinically proven amount of 0.32% of total fatty acids, the same amount as the worldwide breast milk average2,†, and double the amount found in the leading competitor’s product:
    • Clinically proven to support mental and visual development
    • Clinically shown to improve long-term cognitive outcomes through 5 years of age1,§
    • Shown to improve respiratory health through the first 3 years of life when infants were fed through 12 months3,§
  • A blend of 2 prebiotics, GOS (galactooligosaccharides) and PDX (polydextrose), at 4 g/L is clinically proven to:
    • Support immune health by promoting the growth of beneficial bacteria (bifidobacteria and lactobacilli)4,5
    • Promote soft stools similar to those reported for breastfed infants6
  • Clinically proven growth similar to breastfed infants through 12 months7,§
  • Easy-to-digest 60:40 whey-to-casein ratio, patterned after mature breast milk8,*
  • Kosher

* Comparison based on whey-to-casein ratio of typical mature breast milk (15 days to 6 months after birth).

† Studies compared infants fed Enfamil with DHA and ARA vs. discontinued Enfamil without DHA and ARA; studied before the addition of prebiotics.

‡ Average amount of DHA in worldwide breast milk is 0.32% ± 0.22% (mean ± standard deviation of total fatty acids) based on an analysis of 65 studies of 2,474 women2.

§ Enfamil Infant has not been shown superior to the leading competitor in supporting mental, visual and immune system development. The level of DHA in Similac Pro-Advance is ~0.15% of total fatty acids.

  • Nutrients
    • (Normal Dilution)

      Per 100 Calories (5 fl oz)

      Per 100 mL

      Per 100 grams Powder (510 Cal)

      Protein, g

      2

      1.35

      10.1

      Fat, g

      5.3

      3.6

      27

      Linoleic acid, mg

      800

      540

      4000

      Carbohydrate, g

      11.3

      7.6

      57

      Water, g

      133

      90

      2.3

      Vitamins/Other Nutrients

      Vitamin A, IU

      300

      200

      1520

      Vitamin D, IU

      60

      41

      300

      Vitamin E, IU

      2

      1.35

      10.1

      Vitamin K, mcg

      9

      6.1

      45

      Thiamin (Vitamin B1), mcg

      80

      54

      400

      Riboflavin (Vitamin B2), mcg

      140

      95

      710

      Vitamin B6, mcg

      60

      41

      300

      Vitamin B12, mcg

      0.3

      0.2

      1.52

      Niacin, mcg

      1000

      680

      5100

      Folic acid (Folacin), mcg

      16

      10.8

      81

      Pantothenic acid, mcg

      500

      340

      2500

      Biotin, mcg

      3

      2

      15.2

      Vitamin C (Ascorbic acid), mg

      12

      8.1

      61

      Choline, mg

      24

      16.2

      121

      Inositol, mg

      6

      4.1

      30

      Minerals

      Calcium, mg

      78

      53

      390

      Phosphorus, mg

      43

      29

      220

      Magnesium, mg

      8

      5.4

      40

      Iron, mg

      1.8

      1.22

      9.1

      Zinc, mg

      1

      0.68

      5.1

      Manganese, mcg

      15

      10.1

      76

      Copper, mcg

      75

      51

      380

      Iodine, mcg

      15

      10.1

      76

      Selenium, mcg

      2.8

      1.89

      14.1

      Sodium, mg

      27

      18.3

      136

      Potassium, mg

      108

      73

      550

      Chloride, mg

      63

      43

      320

      Product nutrient values and ingredients are subject to change. Please see product label for current information.

  • Nutrient Facts
    • Nutrient Density

      20 Calories/fl oz

      Protein (% Calories)

      8

      Whey:Casein Ratio

      60:40

      Fat (% Calories)

      48

      Carbohydrate (% Calories)

      44

      Potential Renal Solute Load (mOsm/100 Calories)9

      18.6

      Potential Renal Solute Load (mOsm/100 mL)9

      12.5

      Osmolality (mOsm/kg water)

      300

      Osmolarity (mOsm/L)

      270

      Lactose-free

      No

  • Product Forms

      Enfamil® Infant is available in powder and concentrate.

      When using this information, please note the following:

      Coding systems and reimbursement allowable rates vary by payer:

      • Medicare Part B uses HCPCS (Healthcare Common Procedure Coding System) to group products
      • Medicaid systems vary by state; some use HCPCS while others use NDC format code or systems of their own—contact your state provider for more information
      • Private health insurance and managed care companies may use HCPCS, NDC format code or their own system—contact your provider for more information

    • Product: Enfamil® Infant
      Item #: 1365A7
      Description: Powder
      Unit Size: 30 oz can
      Calories/Unit: 4300
      Product Yield/Unit (fl oz): 215
      Case: 4 cans per case
      HCPCS Code: B4158
      NDC Format Code: 00087-5121-27
    • Product: Enfamil Infant
      Item #: 1365A5
      Description: Powder
      Unit Size: 21.1 oz can
      Calories/Unit: 3020
      Product Yield/Unit (fl oz): 151
      Case: 4 cans per case
      HCPCS Code: B4158
      NDC Format Code: 00087-5119-76
    • Product: Enfamil Infant
      Item #: 136701
      Description: Concentrate
      Unit Size: 13 fl oz can
      Calories/Unit: 520
      Product Yield/Unit (fl oz): 26
      Case: 12 cans per case
      HCPCS Code: B4158
      NDC Format Code: 00087-1367-41
    • Product: Enfamil Infant
      Item #: 136502
      Description: Powder
      Unit Size: 12.5 oz can
      Calories/Unit: 1800
      Product Yield/Unit (fl oz): 90
      Case: 6 cans per case
      HCPCS Code: B4158
      NDC Format Code: 00087-1365-42
    • Product: Enfamil Infant
      Item #: 170901
      Description: RTU
      Unit Size: 8 fl oz bottle
      Calories/Unit: 160
      Product Yield/Unit (fl oz): 8
      Case: 24 bottles per case
      HCPCS Code: B4158
      NDC Format Code: 00087-5102-42
    • Product: Enfamil Infant
      Item #: 172501
      Description: RTU
      Unit Size: 32 fl oz bottle
      Calories/Unit: 640
      Product Yield/Unit (fl oz): 32
      Case: 6 bottles per case
      HCPCS Code: B4158
      NDC Format Code: 00087-5121-54
  • Composition
    • Ingredients: Powder: Nonfat milk, lactose, vegetable oil (palm olein, coconut, soy and high oleic sunflower oils), whey protein concentrate and less than 2%: galactooligosaccharides*, polydextrose*, Mortierella alpina oil, Crypthecodinium cohnii oil, calcium carbonate, potassium citrate, ferrous sulfate, potassium chloride, magnesium oxide, sodium chloride, zinc sulfate, cupric sulfate, manganese sulfate, potassium iodide, sodium selenite, soy lecithin, choline chloride, ascorbic acid, niacinamide, calcium pantothenate, vitamin A palmitate, vitamin B12, vitamin D3, riboflavin, thiamin hydrochloride, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, inositol, vitamin E acetate, nucleotides (cytidine 5’-monophosphate, disodium uridine 5’-monophosphate, adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate), taurine, L-carnitine.

      Ingredients: Concentrate: Water, nonfat milk, lactose, vegetable oil (palm olein, soy, coconut and high oleic sunflower oils) and less than 2%: galactooligosaccharides*, polydextrose*, Mortierella alpina oil, Crypthecodinium cohnii oil, whey protein concentrate, potassium citrate, calcium carbonate, calcium phosphate, magnesium phosphate, calcium chloride, sodium chloride, ferrous sulfate, sodium citrate, zinc sulfate, cupric sulfate, manganese sulfate, potassium iodide, sodium selenite, soy lecithin, mono- and diglycerides, ascorbic acid, sodium ascorbate, vitamin E acetate, niacinamide, calcium pantothenate, vitamin A palmitate, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, vitamin D3, vitamin B12, choline chloride, carrageenan, inositol, nucleotides (cytidine 5’ monophosphate, disodium uridine 5’-monophosphate, adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate), taurine, L-carnitine.

      * A type of prebiotic.

      † A source of arachidonic acid (ARA).

      ‡ A source of docosahexaenoic acid (DHA).

  • Potential Allergens
    • Enfamil Infant contains milk and soy.

  • Amino Acid Composition
    • ESSENTIAL AMINO ACIDS

      mg/100 Cal

      mg/100 g Pwd

      Histidinne

      50

      250

      Isoleucine

      116

      590

      Leucine

      210

      1080

      Lysine

      180

      910

      Methionine

      46

      230

      Cysteine

      36

      184

      Phenylalanine

      84

      420

      Tyrosine

      80

      400

      Threonine

      122

      620

      Tryptophan

      35

      177

      Valine

      122

      620

      NONESSENTIAL AMINO ACIDS

      mg/100 Cal

      mg/100 g Pwd

      Arginine

      60

      300

      Alanine

      88

      440

      Aspartic Acid

      200

      990

      Glutamic Acid

      400

      2000

      Glycine

      40

      200

      Proline

      160

      810

      Serine

      114

      580

  • Preparation of Feedings
    • Powder

      The baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant
      formula. Powdered infant formulas are not sterile and should NOT be fed to premature infants or infants who might have immune problems unless directed and supervised by a doctor. Discuss with parents which formula is
      appropriate for the baby.

      Discuss with parents whether they need to use cooled, boiled water for mixing and whether they need to boil clean utensils, bottles and nipples in water before use.

      WARNING: Do not use a microwave oven to warm formula. Serious burns may result.

      Refer to the product label for the most accurate information.

      Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within 1 hour or discard.

      1. Wash hands thoroughly with soap and water before preparing formula.
      2. Pour the desired amount of water into the bottle. Add powder.
      3. Cap bottle and SHAKE WELL.

      Use the following chart for correct amounts of water and powder. Use scoop in tub or can to measure powder. Store DRY scoop in lid holder in tub or in can.

      Enfamil Infant

      To Make*

      Water

      Powder

      Weight

      2 fl oz bottle

      2 fl oz

      1 unpacked level scoop

      8.8 g

      4 fl oz bottle

      4 fl oz

      2 unpacked level scoops

      17.6 g

      8 fl oz bottle

      8 fl oz

      4 unpacked level scoops

      35.2 g

      * Each scoop adds about 0.2 fl oz to the amount of prepared formula.

    • Concentrate

      The baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby.

      13 fl oz Cans

      1. Wash hands thoroughly with soap and water before preparing formula.
      2. Clean can lid, SHAKE CAN WELL and open.
      3. Pour desired amount of water into the bottle. Add an equal amount of concentrated liquid. Shake or stir well.


      WARNING: Do not use a microwave oven to warm formula. Serious burns may result.

      Failure to follow these instructions could result in severe harm. Opened bottles or cans can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use opened containers and/or prepared formula if they are unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use prepared formula within 1 hour or discard.

    • Ready-to-Use

      The baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby.

      8 fl oz Bottles

      1. Wash hands thoroughly with soap and water before preparing feeding bottles.
      2. SHAKE BOTTLE WELL, remove protective seal around cap, remove cap and foil seal.
      3. Pour into feeding bottle(s).


      WARNING: Do not use a microwave oven to warm formula. Serious burns may
      result.



      Failure to follow these instructions could result in severe harm. Opened bottles can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use opened bottle and/or prepared formula if they are unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use prepared formula within 1 hour or discard.

  • References
      1. Colombo J, Carlson SE, Cheatham CL, et al. Long-term effects of LCPUFA supplementation on childhood cognitive outcomes. Am J Clin Nutr. 2013;98:403-412.
      2. Brenna JT, Varamini B, Jensen RG, et al. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr. 2007;85:1457-1464.
      3. Birch EE, Khoury JC, Berseth CL, et al. The impact of early nutrition on incidence of allergic manifestations and common respiratory illnesses in children. J Pediatr. 2010;156:902-906.
      4. Scalabrin D, Mitmesser SH, Welling GW, et al. New prebiotic blend of polydextrose and galacto-oligosaccharides has a bifidogenic effect in young infants. J Pediatr Gastroenterol Nutr. 2012;54:343-352.
      5. Salminen S, Endo A, Isolauri E, et al. Early gut colonization with lactobacilli and staphylococcus in infants: the hygiene hypothesis extended. J Pediatr Gastroenterol Nutr. 2016;62:80-86.
      6. Ziegler E, Vanderhoof JA, Petschow B, et al. Term infants fed formula supplemented with selected blends of prebiotics grow normally and have soft stools similar to those reported for breast-fed infants. J Pediatr Gastroenterol Nutr. 2007;44:359-364.
      7. Ferguson PW, Mitmesser SH, Maharaj N, et al. How is baby doing? Growth of US and Canadian infants using the Centers for Disease Control and Prevention and World Health Organization charts. Nutr Today. 2007;42:151-159.
      8. Kunz C, Lönnerdal B. Re-evaluation of the whey protein/casein ratio of human milk. Acta Paediatr. 1992;81:107-112.
      9. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy. J Pediatr. 1999;134:11-14.
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