• A medical food powder for children and adults with homocystinuria.


A medical food powder for children and adults with homocystinuria.

Last Updated: Monday, October 5, 2015

  • Indication
    • HCY 2 is a medical food powder that is free of the essential amino acid methionine for children and adults with homocystinuria. The product provides all other essential amino acids as well as nonessential amino acids, carbohydrate, fat, essential fatty acids, vitamins and minerals. Use under direct and continuing supervision of a doctor.

  • Product Features
      • Methionine-free

      • Cystine level is similar to the sum of cystine and methionine found in cow's milk

      • 22 g protein equivalents/100 g powder

      • Suitable for someone with lactose intolerance

      • Vanilla scent

      • Can be easily modified with preferred flavor enhancers

      • Mixes easily and stays in suspension well

      • Vitamin and mineral levels appropriate for children and adults

  • Nutrients*
    • Per 100 grams Powder
      Calories 410
      Protein equivalent, g 22
      Fat, g 8.5
      Linoleic acid, mg 4200
      Linolenic acid, mg 520
      Carbohydrate, g 61
      Per 100 grams Powder
      Vitamins ⁄ Other Nutrients
      Vitamin A, IU 1730
      Vitamin D, IU 350
      Vitamin E, IU 12.2
      Vitamin K, mcg 47
      Thiamin (Vitamin B1), mcg 1430
      Riboflavin (Vitamin B2), mcg 1140
      Vitamin B6, mcg 1140
      Vitamin B12, mcg 2.9
      Niacin, mcg 26000
      Folic acid (Folacin), mcg 410
      Pantothenic acid, mcg 5700
      Biotin, mcg 57
      Vitamin C (Ascorbic acid), mg 57
      Choline, mg 98
      Inositol, mg 57
      Taurine, mg 57
      Carnitine, mg 49
      Per 100 grams Powder
      Calcium, mg 730
      Phosphorus, mg 730
      Magnesium, mg 163
      Iron, mg 13.8
      Zinc, mg 13.8
      Manganese, mcg 1500
      Copper, mcg 1430
      Iodine, mcg 63
      Selenium, mcg 33
      Sodium, mg 590
      Potassium, mg 1100
      Chloride, mg 960
      Molybdenum, mcg 45
      Chromium, mcg 45

      * Product nutrient values and ingredients are subject to change. Please see product label for current information. † Protein is incomplete since it does not contain the essential amino acid methionine.

  • Nutrient Facts
    • Protein Equivalent (% Calories) 22
      Fat (% Calories) 19
      Carbohydrate (% Calories) 59
      Lactose-Free Suitable for someone with lactose intolerance
      Galactose-Free Yes

      † Protein is incomplete since it does not contain the essential amino acid methionine.

  • Product Form
    • HCY 2 is available in powder.

      Item #: 891901
      Description: Powder
      Unit Size: 1 lb can
      Cal./Unit: 1860
      Prod. Yield / Unit (fl oz): Varies
      Case: 6 cans per case
      HCPCS Code: B4157 or B4162
      Reimbursement Code: 00087-510027

      HCPCS Code

  • Composition
    • Ingredients: Corn syrup solids, amino acids (L-glutamine, L-leucine, L-lysine hydrochloride, potassium aspartate, L-proline, L-valine, L-isoleucine, L-alanine, L-arginine, L-threonine, L-phenylalanine, L-tyrosine, L-serine, L-cystine, glycine, L-histidine, L-tryptophan), sugar, soy oil, modified corn starch, calcium phosphate, sodium citrate, magnesium phosphate, potassium chloride, and less than 1%: sodium phosphate, potassium citrate, choline chloride, ascorbic acid, taurine, inositol, ferrous sulfate, L-carnitine, zinc sulfate, niacinamide, vitamin E acetate, vitamin A palmitate, calcium pantothenate, cupric sulfate, manganese sulfate, vitamin B12, thiamin hydrochloride, vitamin B6 hydrochloride, riboflavin, folic acid, vitamin D3, chromic chloride, sodium molybdate, sodium selenite, sodium iodide, biotin, vitamin K1, ethyl vanillin.

  • Preparation of Feedings
    • Metabolic clinician should consult with patients about the correct amounts of water and powder for consumption. The patient's health depends on carefully following these directions.

      Measure the correct amount of water into a suitable container for mixing. Then add the required amount of HCY 2. Mix well until blended. Consume the prepared beverage immediately or cover and refrigerate. Use within 48 hours of preparation. Mix before drinking.

      Throw away prepared unrefrigerated beverage left in cup within 1 hour after consumption begins.

      Powder Storage (cans)

      Store cans at room temperature. After opening can, keep tightly covered, store in a dry area and use contents within 1 month. Do not freeze powder, and avoid excessive heat. Use by date on bottom of can.


      An unpacked level scoop delivers approximately 14.5 g of powder. Store the DRY scoop in this can.


      This product is nutritionally incomplete. Continuing medical supervision and frequent blood tests are required. Care must be taken to provide enough methionine to support growth, using other foods with this amino acid as required.

      Nutritional powders are not sterile.

      WARNING: Not for parenteral (I.V.) use.

  • Product Characteristics
    • Fat

      Fat provides 19% of total calories in HCY 2. The fat source is soy oil. Soy oil is a source of essential omega-6 and omega-3 fatty acids: linoleic acid and alpha-linolenic acid.


      Protein equivalents provide 22% of total calories in HCY 2. The product provides the essential amino acids (except methionine) as well as nonessential amino acids (see Amino Acids table). Since the product is methionine-free, care must be taken to provide enough methionine from other foods to support growth and tissue maintenance. The high protein equivalent concentration in HCY 2 helps persons with homocystinuria meet their protein needs while consuming fewer calories from the product. This, in turn, allows HCY 2 users to consume a greater variety of foods in order to meet their methionine and calorie needs.

      Essential Amino Acids Per 100 g Powder
      Histidine, mg 550
      Isoleucine, mg 1560
      Leucine, mg 2900
      Lysine, mg 1780
      Methionine, mg 0
      Cystine, mg 810
      Phenylalanine, mg 920
      Tyrosine, mg 920
      Threonine, mg 1030
      Tryptophan, mg 420
      Valine, mg 1720
      Nonessential Amino Acids Per 100 g Powder
      Arginine, mg 1340
      Alanine, mg 1450
      Aspartic acid, mg 1760
      Glutamic acid, mg 3500
      Glycine, mg 790
      Proline, mg 1760
      Serine, mg 880

      ‡ Added as glutamine.


      Carbohydrate provides 59% of total calories in HCY 2. The carbohydrate blend is 52% corn syrup solids, 41% sucrose (table sugar) and 7% modified corn starch. The sucrose in the product helps mask the taste of the amino acids. HCY 2 is suitable for someone with lactose intolerance.

      Vitamins and Minerals

      HCY 2 provides essential vitamins and minerals at levels that are appropriate for children and adults.