• Portagen® - Milk protein-based powder with medium-chain Triglycerides (MCT) for children and adults


Milk protein-based powder with medium-chain Triglycerides (MCT) for children and adults.

Last Updated: Monday, January 23, 2017

Indication: Portagen is a nutritional powder for children and adults with defects in the intraluminal hydrolysis of fat (decreased pancreatic lipase, decreased bile salts); defective mucosal fat absorption (decreased mucosal permeability, decreased absorptive surface); and/or defective lymphatic transport of fat (ie, intestinal lymphatic obstruction).

Portagen is not recommended for use as an infant formula.

Long-Term Usage: Portagen powder is not nutritionally complete. If used long term, supplementation of essential fatty acids and ultra-trace minerals should be considered.

  • Product Features
      • 87% of fat from medium-chain triglycerides

      • Corn oil provides linoleic acid

  • Nutrients*
    • (Normal Dilution) Prepared Beverage
      Per 100 grams Powder per quart (30 Calories ⁄ fl oz) % RDI (per quart)
      Calories 470 960
      Protein, g 16.5 34 68
      Fat, g 22 46
      Linoleic acid, mg 1620 3300
      Cholesterol, mg 4 8.1
      Carbohydrate, g 54 110
      Dietary Fiber, g 0 0
      Water, g 3 820
      (Normal Dilution) Prepared Beverage
      Per 100 grams Powder per quart (30 Calories ⁄ fl oz) % RDI (per quart)
      Vitamins ⁄ Other Nutrients
      Vitamin A, IU 3700 7500 150
      Vitamin D, IU 370 750 188
      Vitamin E, IU 14.7 30 100
      Vitamin K, mcg 74 150 188
      Thiamin (Vitamin B1), mg 0.74 1.5 100
      Riboflavin (Vitamin B2), mg 0.88 1.8 106
      Vitamin B6, mg 0.98 2 100
      Vitamin B12, mcg 2.9 6 100
      Niacin, mg 9.8 20 100
      Folic acid (Folacin), mcg 74 150 38
      Pantothenic acid, mg 4.9 10 100
      Biotin, mcg 37 75 25
      Vitamin C (Ascorbic acid), mg 38 78 130
      Choline, mg 61 125
      Inositol, mg 22 45
      (Normal Dilution) Prepared Beverage
      Per 100 grams Powder per quart (30 Calories ⁄ fl oz) % RDI (per quart)
      Calcium, mg 440 900 90
      Phosphorus, mg 330 680 68
      Magnesium, mg 98 200 50
      Iron, mg 8.8 18 100
      Zinc, mg 4.4 9 60
      Manganese, mg 0.59 1.2 60
      Copper, mg 0.74 1.5 75
      Iodine, mcg 34 70 47
      Selenium, mcg NA NA NA
      Sodium, mg 260 530
      Potassium, mg 590 1200
      Chloride, mg 410 830

      * Product nutrient values and ingredients are subject to change. Please see product label for current information.

      † Percent Daily Value (DV).

      ‡ Reference Daily Intake (RDI) not established.

      NA = None Added

  • Nutrient Facts
    • Nutrient Density At 30 Calories ⁄ fl oz
      Protein (% Calories) 14
      Fat (% Calories) 40
      Carbohydrate (% Calories) 46
      Potential Renal Solute Load (mOsm/L)1 300
      Osmolality (mOsm/kg water) 350
      Osmolarity (mOsm/L formula) 300
      Total Calorie:Nitrogen Ratio 180:1
      Nonprotein Calorie:Nitrogen Ratio 155:1
      Water (g/L) 870
      Lactose-free Suitable for someone with lactose intolerance§
      Low-Residue Yes

      § Not suitable for persons with galactosemia.

  • Product Form
    • Portagen® is available in powder.

      Item #: 038722
      Description: Powder
      Unit Size: 410g can
      Cal./Unit: 1920
      Prod. Yield / Unit (fl oz): 64
      Case: 6 cans per case
      Reimbursement Code: 0087-511728

  • Composition
    • Ingredients: Powder: Corn syrup solids, medium‑chain triglycerides (MCT) oil, sodium caseinate, sugar, corn oil, and less than 2%: vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium citrate, calcium phosphate, magnesium phosphate, ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, sodium iodide, potassium citrate, potassium chloride, taurine, L‑carnitine, soy lecithin.

  • Potential Allergens
    • Portagen contains milk protein.

  • Preparation of Feedings
    • Improper hygiene, preparation, dilution, use or storage may result in severe harm. This product is not recommended for use as an infant formula. Nutritional powders are not sterile and should not be fed to premature infants or those persons who might have immune problems unless directed and supervised by a medical professional.


      1. Wash hands thoroughly with soap and water before preparing formula.

      2. Pour desired amount of water into bottle or cup. Add powder.

      3. Cap bottle and SHAKE WELL.

      Use the following chart for correct amounts of water and powder. Use scoop in can to measure powder. Store DRY scoop in its original can.

      To Make|| Water Powder Weight
      4.5 fl oz 4 fl oz 3 packed level scoops 28.2 g
      1 qt 27 fl oz 1 ⅔ packed level household measuring cups 203 g

      || Each scoop adds about 0.2 fl oz to the amount of prepared formula.

      Failure to follow these instructions could result in severe harm. Once prepared, product can spoil quickly. Either consume immediately or cover and store in refrigerator at 35°-40°F (2°-4°C) for no longer than 24 hours. Shake well before each use. Do not use prepared product if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared product. After feeding begins, do not refrigerate the container; you must use within 1 hour or discard.

      Powder Storage (cans)

      Store cans at room temperature. After opening can, keep tightly covered, store in dry area and use contents within 1 month. Do not freeze powder, and avoid excessive heat. Use by date on bottom of can.


      Portagen® should be used only under the supervision of a physician. It is not nutritionally complete.

      Persons should drink Portagen beverage slowly and start with one or two small servings per day until they become accustomed to the product, since abdominal discomfort and/or diarrhea may occur.

      WARNING: Not for parenteral (I.V.) use.

      Powdered products are not commercially sterile. Nutritional powders should not be used for immunocompromised patients unless clinically required and then under strict medical supervision of preparation and use.

  • Product Characteristics
    • Fat

      The fat content in Portagen® is 40% of total calories. The fat blend is 87% medium-chain triglycerides (MCTs) and 13% corn oil.

      Medium chain triglycerides (MCTs) can help assure that children and adults with fat malabsorption receive an adequate energy supply. MCTs are more easily and rapidly hydrolyzed and absorbed than long-chain fatty acids by persons with fat malabsorption. Corn oil provides a source of linoleic acid.

      Fatty Acid Distribution in Portagen

      Fatty Acid (Percentage of Fatty Acids)
      C6:0 0.87
      C8:0 62
      C10:0 23.3
      C12:0 0.36
      C16:0 1.63
      C18:0 0.36
      C18:1 3.3
      C18:2 7.6
      C18:3 0.22


      Protein provides 14% of the total calories in Portagen. The protein source is sodium caseinate, a cow's milk protein.


      Carbohydrate provides 46% of the total calories in Portagen. The carbohydrate blend is 75% corn syrup solids and 25% sugar (sucrose). Portagen is suitable for someone with lactose intolerance.

      ¶ Not suitable for persons with galactosemia.

  • Clinical Experience
    • Clinical reports indicate that with its high level of MCT oil, Portagen may be useful in the dietary management of patients with malabsorption and steatorrhea associated with gastrectomy2, intestinal resection2,3, lymphangiectasia4,5, and pancreatic insufficiency2,5. In addition, clinicians report that patients with chyluria6, chylothorax6, and congenital ß–lipoprotein deficiency7 improved with diets high in medium-chain triglycerides.

  • References
    • 1. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy. J Pediatr. 1999;134:11-14.

      2. Pinter KG, McCracken BH, Lamar C, Jr., et al. Fat absorption studies in various forms of steatorrhea. Am J Clin Nutr. 1964;15:293–298.

      3. Zurier RB, Campbell RG, Hashim SA, et al. Use of medium–chain triglyceride in management of patients with massive resection of the small intestine. N Engl J Med. 1966;274:490–493.

      4. Holt PR. Dietary treatment of protein loss in intestinal lymphangiectasia: the effect of eliminating dietary long chain triglycerides on albumin metabolism in this condition. Pediatrics. 1964;34:629–635.

      5. Leyland FC, Fosbrooke AS, Lloyd JK, et al. Use of medium–chain triglyceride diets in children with malabsorption. Arch Dis Child. 1969;44:170–179.

      6. Hashim SA, Roholt HB, Babayan VK, et al. Treatment of chyluria and chylothorax with medium–chain triglyceride. N Engl J Med. 1964;270:756–761.

      7. Isselbacher KJ, Scheig R, Plotkin GR, et al. Congenital beta–lipoprotein deficiency: an hereditary disorder involving a defect in the absorption and transport of lipids. Medicine. (Baltimore). 1964;43:347–61.