Scientific evidence is central to the development of quality products at Mead Johnson. Review the weight of evidence that supports the use of the Enfamil Family of Formulas™.
Long-Chain Polyunsaturated Fatty Acid Supplementation in Infancy Reduces Heart Rate and Positively Affects Distribution of Attention
Colombo J et al. Pediatric Research. 2011;70(4):406-410.
In this prospective, double-blind, randomized trial, learn whether different levels of DHA supplementation affect cognitive performance of infants.
Clinical Response to 2 CommonlyUsed Switch Formulas OccursWithin 1 Day
Carol LB et al. Clinical Pediatrics 48(1):58-65 · November 2008
Abstract: Very fussy or extremely fussy infants were randomized to receive: soy-based formula (Soy: n = 82) or a partially hydrolyzed cow's milk protein (CMP), low-lactose formula (PHF: n = 77) in a multicenter, double-blind, randomized, parallel, prospective 28-day feeding trial. Body weight and infant formula tolerance were reported. Adverse events were recorded throughout the study. A significant reduction in mean scores of fussiness, gas, spit-up, and crying compared with baseline measures was observed in infants who received either Soy or PHF within 1 day of formula intake; improvement in symptoms was sustained by study end. Stool consistency remained constant through day 28 in the PHF group, whereas stools in the Soy group became more firm by day 2 and did not return to prestudy consistency. PHF, with a protein profile patterned more closely on human breast milk, improved symptoms of formula intolerance as well as soy-based formula.
Extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG reduces the occurrence of other allergic manifestations in children with cow’s milk allergy: 3-year randomized controlled trial
Canani R et al. J Allergy Clin Immunol. Published online: December 31, 2016
Clinical review of this parallel-arm randomized controlled trial test whether administration of an extensively hydrolyzed casein formula (EHCF) containing the probiotic Lactobacillus rhamnosus GG (LGG) can reduce the occurrence of other AMs in children with CMA.
Lactobacillus GG Improves Recovery in Infants with Blood in the Stools and Presumptive Allergic Colitis Compared with Extensively Hydrolyzed Formula Alone
Baldassarre ME et al. The Journal of Pediatrics. 2010;156(3):397-401.
Review clinical data from a prospective, double-blind, placebo-controlled trial on the benefits of an extensively hydrolyzed casein formula with LGG culture on improving blood in stool.
Effect of Lactobacillus GG on tolerance acquisition in infants with cow’s milk allergy: A randomized trial
Canani R et al. The Journal of Allergy and Clinical Immunology. 2012;129(2):580-582.
Find clinical results from a randomized trial that demonstrates the effect of LGG culture on helping infants outgrow their cow’s milk protein allergy sooner.
Formula Selection for Management of Children with Cow’s Milk Allergy Influences the Rate of Acquisition of Tolerance: A Prospective Multicenter Study
Canani R et al. The Journal of Pediatrics. 2013;163(3):771-777.
In this independent multicenter study, which evaluated the effect of different dietary management strategies on the duration of cow’s milk protein allergy in children, learn how extensively hydrolyzed casein formula with LGG culture compared with other dietary choices.
Efficacy of a Pre-Thickened Infant Formula: a Multicenter, Double-Blind, Randomized, Placebo-Controlled Parallel Group Trial in 104 Infants with Symptomatic Gastroesophageal Reflux
Vanderhoof JA et al. Clinical Pediatrics. 2003;42:483-495.
Learn about how Enfamil A.R. performed in a well-designed clinical trial that evaluated the efficacy of the pre-thickened formula in infants with gastroesophageal reflux (GER).
Nutrient Intakes of US Infants, Toddlers, and Preschoolers Meet or Exceed Dietary Reference Intakes
Butte NF et al. Journal of American Dietetic Association. 2010;110:S27-S37.
Read results from a cross-sectional survey conducted by the American Dietetic Association that assessed the usual nutrient intake of infants, toddlers, and preschoolers aged 0 to 47 months.
Hypoallergenicity and Effects on Growth and Tolerance of a New Amino Acid-Based Formula with Docosahexaenoic Acid and Arachidonic Acid
Burks W et al. The Journal of Pediatrics. 2008;:3(2):266-271.
Review clinical data from 2 studies that evaluated an amino acid-based formula (AAF) in healthy infants and in infants and children with confirmed cow’s milk allergy. Study 1 examined growth in healthy infants consuming the AAF compared with an extensively hydrolyzed formula, with both docosahexaenoic acid and arachidonic acid. Study 2 evaluate the hypoallergenicity of this new AAF.
Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-protein formula supplemented with bovine milk fat globule membranes: a randomized controlled trial
Infections in Infants Fed Formula Supplemented With Bovine Milk Fat Globule Membrane
Observational studies have shown that even in high-income countries formula-fed infants have a higher incidence of acute otitis media (AOM), and gastrointestinal and respiratory tract infections during the first year of life compared with breast-fed infants.