Cow’s Milk Protein Allergy

  • Cow’s milk protein is a leading cause of food allergy in infants and children younger than 3 years1

    The immature gut of the infant and, in particular, the immature mucosal barrier may contribute to increased antigen transfer intact, an important factor in the development of food allergy.2 The prevalence of cow’s milk allergy (CMA) is approximately 2% to 3% in the infant population with a peak in the first year of life.1

  • Educating the immune system to build oral tolerance

    The ultimate goal in CMA management is building oral tolerance

    • Commonly, infants who have CMA build tolerance to cow’s milk protein by 3-5 years of age
    • Infants low exposure to cow’s milk protein (CMP) sooner may help build oral tolerance to CMP
    • Amino acid formulas lack cow’s milk peptides that can help educate the immune system

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  • Nutramigen with Enflora Canani Study

    More infants build an oral tolerance to cow's milk protein than with other formulas used in the study for cow's milk allergy management.

    Formula selection for management of children with cow milk allergy [CMA] influences the rate of acquisition of tolerance: a prospective multicenter study.

    Study objective

    To prospectively evaluate the effect of various dietary choices on building tolerance in children with CMA.

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  • Refrences: 1. Koletzko S et al. J Pediatr Gastroenterol Nutr. 2012;55:221-229. 2. Majamaa H et al. J Allergy Clin Immunol. 1997;99:179-185.

Helping Infants With Cow's Milk Allergy Build Tolerance

We are pleased to invite you to watch an expert presentation online about infant and toddler nutrition. Watch commentary by Dr. Michael Hart, a professor of pediatrics on managing CMPA and helping infants build tolerance to cow's milk protein.

Program Presenter

Michael H. Hart, MD, MS
Professor of Pediatrics
Director of Pediatric GI/Nutrition
Virginia Tech Carilion School of Medicine in Roanoke, Virginia