Enfamil® EnfaCare®

Milk-based, 22 cal discharge formula for babies who were born prematurely or with low birth weight.

Last Updated: Thursday, January 4, 2018 - 19:00

Description/Indication:

Enfamil EnfaCare is a milk-based, 22 Cal/fl oz, iron-fortified, post-discharge formula with enriched nutrition for infants who were born prematurely or with low birth weight*. Enfamil EnfaCare contains vitamin and mineral levels specially tailored for premature babies’ first year of life after discharge from the hospital. Enfamil EnfaCare is typically used during the first year of life for infants from approximately 1800 g in weight.

* Increased caloric density, protein, and some vitamins and minerals compared to standard term formula to help support weight and growth in babies born prematurely.

Product Features:

  • Clinically proven to promote catch-up growth to help support developmental outcomes during the first year1,†:
    • 2.8 g protein/100 Calories, which is a higher protein level than Enfamil PREMIUM® Infant formula
    • 54% more calcium than Enfamil PREMIUM Infant formula
    • 53% more phosphorus than Enfamil PREMIUM Infant formula
    • 25% more vitamin D than Enfamil PREMIUM Infant formula
  • DHA to promote brain and eye development2-9:
    • DHA at the clinically proven amount of 0.32% of total fatty acids, the same amount as the worldwide breast milk average10,‡
  • 20% of the fat blend from medium-chain triglycerides (MCT) oil
  • 80:20 whey-to-casein ratio patterned after early breast milk11,§
  • Has choline to help support brain development
  • Kosher (powder and ready-to-use), Halal (ready-to-use)


* Increased caloric density, protein, and some vitamins and minerals compared to standard term formula to help support weight and growth in babies born prematurely.

† When used in a program of Enfamil® formulas: Enfamil® Premature, Enfamil EnfaCare and Enfamil Infant.

‡ Average amount of DHA in worldwide breast milk is 0.32% ± 0.22% (mean ± standard deviation of total fatty acids) based on an analysis of 65 studies of 2,474 women10.

§ Based on whey-to-casein ratio 3-5 days after lactation begins.

  • Nutrients
    • (Normal Dilution)

      Per 100 Cal

      Per 100 mL

      Protein, g

      2.8

      2.1

      Fat, g

      5.3

      3.9

      Linoleic acid, mg

      860

      640

      Carbohydrate, g

      10.4

      7.7

      Water, g

      120

      89

      Vitamins/Other Nutrients

      Vitamin A, IU

      450

      330

      Vitamin D, IU

      75

      56

      Vitamin E, IU

      4

      3

      Vitamin K, mcg

      9

      6.7

      Thiamin (Vitamin B1), mcg

      180

      133

      Riboflavin (Vitamin B2), mcg

      200

      148

      Vitamin B6, mcg

      67

      50

      Vitamin B12, mcg

      0.3

      0.22

      Niacin, mcg

      1000

      740

      Folic acid (Folacin), mcg

      26

      19.3

      Pantothenic acid, mcg

      850

      630

      Biotin, mcg

      6

      4.4

      Vitamin C (Ascorbic acid), mg

      16

      11.9

      Choline, mg

      24

      17.8

      Inositol, mg

      24

      17.8

      Minerals

      Calcium, mg

      120

      89

      Phosphorus, mg

      66

      49

      Magnesium, mg

      8

      5.9

      Iron, mg

      1.8

      1.33

      Zinc, mg

      1

      0.74

      Manganese, mcg

      15

      11.1

      Copper, mcg

      90

      67

      Iodine, mcg

      21

      15.6

      Selenium, mcg

      2.8

      2.1

      Sodium, mg

      37

      27

      Potassium, mg

      105

      78

      Chloride, mg

      78

      58

      Product nutrient values and ingredients are subject to change. Please see product label for current information.

  • Nutrient Facts
    • Nutrient Density

      22 Calories/fl oz Pwd

      22 Calories/fl oz Liquid

      Protein (% Calories)

      11

      11

      Fat (% Calories)

      47

      47

      Carbohydrate (% Calories)

      42

      42

      Potential Renal Solute Load (mOsm/100 Calories)12

      25

      25

      Potential Renal Solute Load (mOsm/100 mL)12

      18.4

      18.4

      Osmolality (mOsm/kg water)

      310

      230

      Osmolarity (mOsm/L)

      270

      200

      Lactose-free

      No

      No

  • Product Forms

      Enfamil EnfaCare is available in powder, ready-to-use liquid and Nursette® bottles.

      When using this information, please note the following:

      Coding systems and reimbursement allowable rates vary by payer:

      • Medicare Part B uses HCPCS (Healthcare Common Procedure Coding System) to group products
      • Medicaid systems vary by state; some use HCPCS while others use NDC format code or systems of their own—contact your state provider for more information
      • Private health insurance and managed care companies may use HCPCS, NDC format code or their own system—contact your provider for more information

    • Product: Enfamil EnfaCare
      Item #: 149501
      Description: RTU
      Unit Size: 8 fl oz bottle
      Calories/Unit: 176
      Product Yield/Unit (fl oz): 8
      Case: 24 bottles per case
      HCPCS Code: B4160
      NDC Format Code: 00087-5102-98
  • Composition
    • Ingredients: Ready To Use (8 fl oz bottle): Water, nonfat milk, maltodextrin, lactose, whey protein concentrate, high oleic sunflower oil, soy oil, medium chain triglycerides (MCT oil), coconut oil and less than 0.5%: Mortierella alpina oil||, Crypthecodinium cohnii oil, mono- and diglycerides, soy lecithin, calcium phosphate, calcium hydroxide, potassium citrate, calcium citrate, magnesium chloride, sodium chloride, potassium chloride, sodium citrate, ferrous sulfate, zinc sulfate, cupric sulfate, potassium iodide, manganese sulfate, sodium selenite, rice starch, sodium ascorbate, ascorbic acid, vitamin E acetate, niacinamide, calcium pantothenate, thiamin hydrochloride, vitamin A palmitate, riboflavin, vitamin B6 hydrochloride, folic acid, vitamin D3, vitamin K1, biotin, vitamin B12, choline chloride, inositol, nucleotides (cytidine 5’-monophosphate, disodium uridine 5’-monophosphate, adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate), taurine, L-carnitine.

      || A source of arachidonic acid (ARA).

      ¶ A source of docosahexaenoic acid (DHA).

  • Potential Allergens
    • Enfamil® EnfaCare® contains milk and soy.

  • Amino Acid Composition
    • ESSENTIAL AMINO ACIDS
      mg/100 Calmg/100 g Pwd
      Histidine64320
      Isoleucine171850
      Leucine3101530
      Lysine2601290
      Methionine62310
      Cysteine64320
      Phenylalanine106530
      Tyrosine98490
      Threonine193960
      Tryptophan54270
      Valine171850
      NONESSENTIAL AMINO ACIDS
      mg/100 Calmg/100 g Pwd
      Arginine78390
      Alanine137680
      Aspartic Acid3001490
      Glutamic Acid5402700
      Glycine56280
      Proline200990
      Serine160790
      Tyrosine98490
      Threonine193960
      Tryptophan54270
      Valine171850
  • Preparation of Feedings
    • Ready-to-Use

      The baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby.

      8 fl oz Bottles

      1. Wash hands thoroughly with soap and water before preparing feeding bottles.
      2. SHAKE BOTTLE WELL, remove protective seal around cap, remove cap and foil seal.
      3. Pour into feeding bottle(s).

      WARNING: Do not use a microwave oven to warm formula. Serious burns may result.

      Failure to follow these instructions could result in severe harm. Opened bottles and prepared formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use opened bottle and/or prepared formula if they are unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use prepared formula within 1 hour or discard.

  • References
      1. Clandinin MT, Van Aerde JE, Merkel KL, et al. Growth and development of preterm infants fed infant formulas containing docosahexaenoic acid and arachidonic acid. J Pediatr. 2005;146:461–468.
      2. Birch EE, Hoffman DR, Uauy R, et al. Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr Res. 1998;44:201–209.
      3. Birch EE, Garfield S, Hoffman DR, at al. A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants. Dev Med Child Neurol. 2000;42:174–181.
      4. Birch EE, Hoffman DR, Castañeda YS, et al. A randomized controlled trial of long-chain polyunsaturated fatty acid supplementation of formula in term infants after weaning at 6 wk of age. Am J Clin Nutr. 2002;75:570–580.
      5. Hoffman DR, Birch EE, Castañeda YS, et al. Visual function in breast-fed term infants weaned to formula with or without long-chain polyunsaturates at 4 to 6 months: a randomized clinical trial. J Pediatr. 2003;142(6):669–677.
      6. Hoffman DR, Birch EE, Castaneda YS, et al. Maturation of visual and mental function in 18-month-old infants receiving dietary long-chain polyunsaturated fatty acids [abstract]. FASEB J. 2003;17:A727–A728. Abstract 445.1.
      7. Hoffman DR, Birch EE, Birch DG, et al. Impact of early dietary intake and blood lipid composition of long-chain polyunsaturated fatty acids on later visual development. J Pediatr Gastroenterol Nutr. 2000;31:540-553.
      8. Birch EE, Castañeda YS, Wheaton DH, et al. Visual maturation of term infants fed long-chain polyunsaturated fatty acid-supplemented or control formula for 12 mo. Am J Clin Nutr. 2005;81:871-879.
      9. Morale SE, Hoffman DR, Castañeda YS, et al. Duration of long-chain polyunsaturated fatty acids availability in the diet and visual acuity. Early Hum Dev. 2005;81:197-203.
      10. Brenna JT, Varamini B, Jensen RG, et al. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr. 2007;85:1457-1464.
      11. Kunz C, Lönnerdal B. Re-evaluation of the whey protein/casein ratio of human milk. Acta Paediatr. 1992;81:107-112.
      12. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute in infancy. J Pediatr. 1999;134:11-14.
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