• Medical food powder for children and adults with propionic or methylmalonic acidemia (organic acidemia).

OA 2

Medical food powder for children and adults with propionic or methylmalonic acidemia (organic acidemia).

Last Updated: Monday, October 5, 2015

Indication: OA 2 is a medical food powder that is free of the essential amino acids isoleucine, methionine, threonine, and valine for children and adults with propionic or methylmalonic acidemia (organic acidemia). The product provides all other essential amino acids as well as nonessential amino acids, carbohydrate, fat, essential fatty acids, vitamins and minerals. Use under direct and continuing supervision of a doctor.

  • Product Features
      • Isoleucine-, methionine-, threonine-, and valine-free

      • Provides adequate protein, linoleic and linolenic acid, and vitamins and minerals not available from low-protein foods while supplying fewer calories than OA 1

      • The protein source is a mixture of L-amino acids optimized for blandness, free of isoleucine, methionine, threonine, and valine

      • 21 g protein equivalent*/100 g powder

      • Fat comprises approximately 20% of total Calories (9 g/100 g powder)

      • Vanilla scent

      • Can be easily modified with preferred flavor enhancers

      • Mixes easily and stays in suspension well

      * Protein is incomplete since it does not contain the essential amino acids isoleucine, methionine, threonine, and valine.

  • Nutrients
    • Per 100 grams Powder
      Calories 410
      Protein equivalent, g* 21
      Fat, g 9
      Linoleic acid, mg 4400
      Linolenic acid, mg 550
      Carbohydrate, g 59
      Per 100 grams Powder
      Vitamins/Other Nutrients
      Vitamin A, IU 1430
      Vitamin D, IU 290
      Vitamin E, IU 10.3
      Vitamin K, mcg 41
      Thiamin (Vitamin B1), mcg 1200
      Riboflavin (Vitamin B2), mcg 980
      Vitamin B6, mcg 980
      Vitamin B12, mcg 2.4
      Niacin, mcg 22000
      Folic acid (Folacin), mcg 350
      Pantothenic acid, mcg 4800
      Biotin, mcg 49
      Vitamin C (Ascorbic acid), mg 49
      Choline, mg 102
      Inositol, mg 49
      Taurine, mg 49
      Carnitine, mg 49
      Per 100 grams Powder
      Minerals
      Calcium, mg 760
      Phosphorus, mg 760
      Magnesium, mg 177
      Iron, mg 12.3
      Zinc, mg 12.3
      Manganese, mcg 1350
      Copper, mcg 1220
      Iodine, mcg 66
      Selenium, mcg 27
      Sodium, mg 610
      Potassium, mg 1160
      Chloride, mg 1060
      Molybdenum, mcg 37
      Chromium, mcg 37

      * Protein is incomplete since it does not contain the essential amino acids isoleucine, methionine, threonine and valine. † Product nutrient values and ingredients are subject to change. Please see product label for current information.

  • Nutrient Facts
    • Protein Equivalent (% Calories)* 21
      Fat (% Calories) 20
      Carbohydrate (% Calories) 59
      Potential Renal Solute Load (mOsm/100g powder) 230
      Lactose-Free Suitable for someone with lactose intolerance
      Galactose-Free Yes

      * Protein is incomplete since it does not contain the essential amino acids isoleucine, methionine, threonine, and valine.

  • Product Form
    • OA 2 is available in powder.

      Item #: 891701
      Description: Powder
      Unit Size: 1 lb can
      Cal./Unit: 1860
      Prod. Yield / Unit (fl oz): Varies
      Case: 6 cans per case
      HCPCS Code: B4157 or B4162
      Reimbursement Code: 00087-510022

      HCPCS Code

  • Composition
    • Ingredients: Corn syrup solids, sugar, amino acids (L-alanine, L-leucine, L-lysine hydrochloride, potassium aspartate, L-proline, L-arginine, glycine, L-phenylalanine, L-tyrosine, L-serine, L-histidine, L-tryptophan, L-cystine), soy oil, modified corn starch, calcium phosphate, sodium citrate, magnesium phosphate, potassium chloride, and less than 1%: sodium phosphate, potassium citrate, choline chloride, ascorbic acid, taurine, inositol, ferrous sulfate, L-carnitine, zinc sulfate, niacinamide, vitamin E acetate, vitamin A palmitate, calcium pantothenate, cupric sulfate, manganese sulfate, vitamin B12, thiamin hydrochloride, vitamin B6 hydrochloride, riboflavin, folic acid, vitamin D3, chromic chloride, sodium molybdate, sodium iodide, sodium selenite, biotin, vitamin K1, ethyl vanillin.

  • Preparation of Feedings
    • The patient's health depends on carefully following these directions. Use only as directed by a medical professional. Improper hygiene, preparation, dilution, use or storage may result in severe harm. Powder medical foods are not sterile and should not be fed to those persons who might have immune problems unless directed and supervised by a medical professional.

      Metabolic clinician should consult with patients about the correct amounts of water and powder for consumption.

      Measure the correct amount of water into a suitable container for mixing. Then add the required amount of OA 2. Mix well until blended. Failure to follow these instructions could result in severe harm. Once prepared, product can spoil quickly. Either consume immediately or cover and store in refrigerator at 35°–40°F (2°–4°C) for no longer than 24 hours. Mix well before each use. Do not use prepared product if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared product. After feeding begins, use within 1 hour or discard.

      Powder Storage (cans)

      Store cans at room temperature. After opening can, keep tightly covered, store in dry area and use contents within 1 month. Do not freeze powder, and avoid excessive heat. Use by date on bottom of can.

      Scoop

      An unpacked level scoop delivers approximately 14.5 g of powder. Store the DRY scoop in this can.

      CAUTION

      This product is nutritionally incomplete. Continuing medical supervision and frequent blood tests are required. Care must be taken to provide enough isoleucine, methionine, threonine and valine to support growth, using other foods with these amino acids as required.

      Nutritional powders are not sterile.

      WARNING: Not for parenteral (I.V.) use.

  • Product Characteristics
    • Fat

      Fat provides 20% of total calories in OA 2. Soy oil is a source of the essential omega-6 to omega-3 fatty acids: linoleic and alpha-linolenic acid.

      Protein

      Protein equivalents provide 20% of total calories in OA 2. Since the product contains no isoleucine, methionine, threonine, or valine, care must be taken to provide enough isoleucine, methionine, threonine and valine from other foods to support growth.

      Amino Acids

      Essential Amino Acids Per 100 g Powder
      Histidine, mg 650
      Isoleucine, mg 0
      Leucine, mg 3400
      Lysine, mg 2100
      Methionine, mg 0
      Cystine, mg 420
      Phenylalanine, mg 1110
      Tyrosine, mg 1110
      Threonine, mg 0
      Tryptophan, mg 480
      Valine, mg 0
      Nonessential Amino Acids Per 100 g Powder
      Arginine, mg 1340
      Alanine, mg 6100
      Aspartic acid, mg 1760
      Glutamic acid, mg 0
      Glycine, mg 1340
      Proline, mg 1760
      Serine, mg 920

      Carbohydrate

      Carbohydrate provides 60% of total calories in OA 2. The carbohydrate blend is 50% corn syrup solids, 43% sucrose (table sugar), and 7% modified corn starch. The sucrose in the product helps neutralize the taste of the amino acids. OA 2 is suitable for someone with lactose intolerance.

      Vitamins and Minerals

      The vitamin and mineral levels are generally appropriate for older children and adults.