The most common food allergy experienced by infants is cow’s milk protein allergy (CMPA)—in fact, an estimated 2–3% of babies experience CMPA1. Excessive crying is common in CMPA, with many episodes of crying lasting 3 hours or more each day2. In addition to colic, babies with CMPA may have frequent regurgitation, occult blood loss and atopic eczema1.
Several steps, including food challenges, are often required to identify CMPA. The ultimate goal of the dietary management of CMPA is not only to modify the course of the allergy, but to build oral tolerance, meaning that the infant does not react negatively to cow’s milk proteins‡.
Nutramigen® with Enflora™ LGG® is clinically proven to work fast to manage colic due to CMPA—often within 48 hours2,§. Nutramigen with Enflora LGG is a nutritionally complete, hypoallergenic formula with easy-to-digest proteins that will support a baby’s development while managing CMPA. In addition, Nutramigen with Enflora LGG is proven to help babies outgrow CMPA in as little as 6 months of feeding3,||.
Nutramigen with Enflora LGG is formulated with extensively hydrolyzed proteins and the probiotic branded LGG. Extensively hydrolyzed proteins, or eHP, are broken down proteins, which helps reduce the exposure to cow’s milk protein. The probiotic branded LGG helps support digestive health4,5. Over time, the baby’s immune system no longer recognizes cow’s milk protein as an antigen.
Most babies who develop CMPA will outgrow their allergy by 3-5 years of age6-8. However, with Nutramigen with Enflora LGG, babies may not have to wait that long. Nutramigen with Enflora LGG is clinically proven to help more infants consume milk proteins after 6-12 months of feeding without an allergic reaction3.
Additionally, Nutramigen with Enflora LGG outperforms other formulas used in the study in helping infants consume milk proteins without an allergic response. Compared to other formulas used in the study, 79% of infants fed Nutramigen with Enflora LGG could consume cow’s milk after 12 months of feeding10.
Nutramigen with Enflora LGG works as first-line management of CMPA. Not only is it clinically proven to manage colic due to CMPA, it does so fast—often within 48 hours2,§.
* LGG is a registered trademark of Valio Ltd.
† WIC is a registered trademark of the United States Department of Agriculture (USDA) for the Women, Infants and Children program. No endorsement of any brand or product by the USDA is implied or intended.
‡ Tolerance is the presence of a negative, double-blind, placebo-controlled food challenge in the study.
§ Studied before the addition of LGG, DHA and ARA.
|| vs naturally outgrowing CMPA in 3-5 years.
¶ eHF without LGG was Nutramigen without LGG culture.
# Study formulas included: Extensively hydrolyzed casein: Nutramigen and Nutriben hydrolyzed; Rice hydrolysate: Risolac; Soy: Isomil, Sinelac, Nutrilon Soya; Amino Acid: Neocate, Nutramigen AA, Sineall.
References: 1. Koletzko S et al. J Pediatr Gastroenterol Nutr. 2012;55:221-229. 2. Lothe L et al. Pediatrics. 1989;83:262-266. 3. Canani RB et al. J Allergy Clin Immunol. 2012;129:580-582. 4. Isolauri E et al. J Clin Gastroenterol. 2008;42(Suppl 2):S91-S96. 5. Baldassarre ME et al. J Pediatr. 2010;156:397-401. 6. Wood RA et al. Pediatrics. 2003;111:1631-1637. 7. Host A et al. Allergy. 1990;45:587-596. 8. Bishop JM et al. J Pediatr. 1990;116:862-867. 9. Berni Canani R. Email. April 23, 2012. 10. Canani RB et al. J Pediatr. 2013;163:771-777.