• Enfamil® Newborn
  • Enfamil® Newborn
  • Enfamil® Newborn
  • Enfamil® Newborn

Enfamil® Newborn

Milk-based infant formula for newborns through 3 Months.

Last Updated: Wednesday, September 30, 2015

Indication: Enfamil Newborn is a milk-based, iron-fortified formula for full-term newborns through 3 months. It has the same trusted nutritional source as Enfamil® Infant and is designed for newborns.

The American Academy of Pediatrics (AAP) recommends that babies get 400 IU of vitamin D daily. Enfamil Newborn provides 400 IU of vitamin D in 27 fl oz—close to the approximate daily intake of a newborn.

  • Product Features
      • A Neuro Complete blend of nutrients that are also found in breast milk
      • Has a DHA and ARA blend shown* to foster a child’s learning ability up to age 51
      • Provides 400 IU of vitamin D in just 27 fl oz—close to the approximate daily intake of a newborn
      • Milk-based infant formula patterned after early breast milk
      • Easy-to-digest, 80:20 whey-to-casein protein blend
      • A dual prebiotics blend—GOS (galactooligosaccharides) and polydextrose—to support the growth of beneficial gut bacteria, which emerging science suggests can help support the immune system2-4
      • The same DHA level as Enfamil Infant, similar to worldwide breast milk averages5,†, to support mental, visual and immune system development

      DHA and ARA Fatty Acid Nutrients

      • DHA – 17 mg
      • ARA – 34 mg

      * Shown in Enfamil Infant with DHA and ARA. † Average level of DHA in worldwide breast milk is 0.32% ± 0.22% (mean ± standard deviation of total fatty acids) based on an analysis of 65 studies of 2,474 women5. ‡ Per 100 Calories.

  • Nutrients§
    • (Normal Dilution) Per 100 Calories (5 fl oz) Per 100 grams Powder (510 Cal)
      Protein, g 2.1 10.8
      Fat, g 5.3 27
      Linoleic acid, mg 860 4400
      Carbohydrate, g 11.2 57
      Water, g 133 2
      (Normal Dilution) Per 100 Calories (5 fl oz) Per 100 grams Powder (510 Cal)
      Vitamins/Other Nutrients
      Vitamin A, IU 300 1540
      Vitamin D, IU 75 380
      Vitamin E, IU 2 10.3
      Vitamin K, mcg 9 46
      Thiamin (Vitamin B1), mcg 80 410
      Riboflavin (Vitamin B2), mcg 140 720
      Vitamin B6, mcg 60 310
      Vitamin B12, mcg 0.3 1.54
      Niacin, mcg 1000 5100
      Folic acid (Folacin), mcg 16 82
      Pantothenic acid, mcg 500 2600
      Biotin, mcg 3 15.4
      Vitamin C (Ascorbic acid), mg 12 62
      Choline, mg 24 123
      Inositol, mg 6 31
      (Normal Dilution) Per 100 Calories (5 fl oz) Per 100 grams Powder (510 Cal)
      Minerals
      Calcium, mg 78 400
      Phosphorus, mg 43 220
      Magnesium, mg 8 41
      Iron, mg 1.8 9.2
      Zinc, mg 1 5.1
      Manganese, mcg 15 77
      Copper, mcg 75 380
      Iodine, mcg 15 77
      Selenium, mcg 2.8 14.4
      Sodium, mg 27 138
      Potassium, mg 108 550
      Chloride, mg 63 320

      § Product nutrient values and ingredients are subject to change. Please see product label for current information.

  • Nutrients Facts
    • Nutrient Density 20 Calories/fl oz
      Protein (% Calories) 8.5
      Fat (% Calories) 48
      Carbohydrate (% Calories) 43.5
      Potential Renal Solute Load (mOsm/100 Calories)5 19.1
      Potential Renal Solute Load (mOsm/100 mL)5 12.9
      Osmolality (mOsm/kg water) 300
      Osmolarity (mOsm/L) 270
      Lactose-Free No
      Galactose-Free No
  • Product Forms
    • Enfamil Newborn is available in powder and ready-to-use liquid.

    • Item #: 146608
      Description: Enfamil Newborn Powder
      Unit Size: 12.5oz can
      Cal./Unit: 1800
      Prod. Yield / Unit (fl oz): 90
      Case: 6 cans per case
      Reimbursement Code: 00087-510050

    • Item #: 146625
      Description: Enfamil Newborn Powder
      Unit Size: 22.2oz Tub
      Cal./Unit: 3220
      Prod. Yield / Unit (fl oz): 161
      Case: 4 tubs per case
      Reimbursement Code: 00087-146645

    • Item #: 146624
      Description: Enfamil Newborn Powder
      Unit Size: 33.2oz box
      Cal./Unit: 4820
      Prod. Yield / Unit (fl oz): 241
      Case: 4 boxes per case
      Reimbursement Code: 00087-510042

    • Item #: 165701
      Description: Enfamil Newborn Nursette® Bottle 20 Cal Ready to Use
      Unit Size: 2 fl oz bottle
      Cal./Unit: 40
      Prod. Yield / Unit (fl oz): 2
      Case: 48 bottles per case
      Reimbursement Code: 00087-165741

  • Composition
    • Ingredients: Powder: Nonfat milk, lactose, vegetable oil (palm olein, coconut, soy and high oleic sunflower oils), whey protein concentrate, galactooligosaccharides||, polydextrose|| and less than 1%: Mortierella alpina oil, Crypthecodinium cohnii oil#, soy lecithin, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, inositol, calcium carbonate, calcium phosphate, magnesium oxide, ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, potassium iodide, sodium selenite, potassium citrate, choline chloride, potassium chloride, sodium chloride, nucleotides (cytidine 5’-monophosphate, disodium uridine 5’-monophosphate, adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate), taurine, L-carnitine.

      Ingredients: Ready To Use: Water, lactose, nonfat milk, vegetable oil (palm olein, soy, coconut and high oleic sunflower oils), whey protein concentrate and less than 1%: galactooligosaccharides||, polydextrose||, Mortierella alpina oil, Crypthecodinium cohnii oil#, mono- and diglycerides, soy lecithin, carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium carbonate, calcium chloride, calcium phosphate, magnesium phosphate, ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, potassium iodide, sodium selenite, sodium ascorbate, sodium citrate, potassium citrate, sodium chloride, nucleotides (cytidine 5’-monophosphate, disodium uridine 5’-monophosphate, adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate), taurine, L-carnitine.

      || A type of prebiotic. ¶ A source of arachidonic acid (ARA). # A source of docosahexaenoic acid (DHA).

  • Potential Allergens
    • Enfamil Newborn contains milk and soy.

  • Preparation of Feedings
    • The baby’s health depends on carefully following these instructions. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Powdered infant formulas are not sterile and should not be fed to premature infants or infants who might have immune problems, unless directed and supervised by a doctor.

      Discuss with parents whether they need to use cooled, boiled water for mixing and whether they need to boil clean utensils, bottles and nipples in water before use.

      POWDER

      1. Wash hands thoroughly with soap and water before preparing formula.
      2. Pour desired amount of water into bottle. Add powder.
      3. Cap bottle and SHAKE WELL.

      Use the following chart for correct amounts of water and powder. Use scoop in can to measure powder. Store DRY scoop in its original can.

      To Make# Water Powder Weight
      2 fl oz 2 fl oz 1 unpacked level scoop 8.7 g
      4 fl oz 4 fl oz 2 unpacked level scoops 17.4 g
      6 fl oz 6 fl oz 3 unpacked level scoops 26.1 g
      8 fl oz 8 fl oz 4 unpacked level scoops 34.8 g
      1 quart 29 fl oz 1 unpacked level household measuring cup + 2 unpacked level Tbsps 125 g

      ** Each scoop adds about 0.2 fl oz to the amount of prepared formula.

      Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in the refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within 1 hour or discard.

      Powder Storage (tubs and pouches)

      Store powder at room temperature; avoid extreme temperatures. Refill pouches can be used with reusable Enfamil Newborn tubs, sold separately. After opening, keep pouch or tub lid tightly closed, store in a dry area and use contents within 1 month. Use with Enfamil Newborn formula only.

      Keep powder fresh and prevent bacterial growth by assuring tub is clean and completely dry. Completely empty tub and wipe clean with a clean, dry cloth before refilling.

      If you choose to empty the pouch into the tub, you must retain the batch code and "use by" date sticker from the pouch.

      Powder Storage (cans)

      Store cans at room temperature. After opening the can, keep it tightly covered, store in a dry area and use the contents within 1 month. Do not freeze powder, and avoid excessive heat. Use by date on the bottom of the can.

      CAUTION

      Use product by date on container. Nutritional powders are not sterile.

      Nursette® Bottles

      1. Inspect each bottle for signs of damage.
      2. Wash hands thoroughly with soap and water before preparing bottle for feeding.
      3. SHAKE BOTTLE WELL and remove cap.
      4. Attach nipple unit (not included).

      Failure to follow these instructions could result in severe harm. Opened bottles can spoil quickly. Either feed immediately or replace cap and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze. After feeding begins, use within 1 hour or discard.

      Nursette Bottle Storage

      Store unopened bottles at room temperature. Avoid excessive heat and prolonged exposure to light. Do not freeze. Use by date on carton and bottle label.

      WARNING: Do not use a microwave oven to prepare or warm formula. Serious burns may result.

  • Product Characteristics
    • Fat

      Enfamil Newborn provides 48% of Calories as fat; similarly, human milk provides approximately 50% of Calories as fat. The fat in Enfamil Newborn is derived primarily from a four-oil fat blend and from single-cell oils. This combination of fats results in a fatty acid profile similar to typical U.S. human milk.

      The fat blend in Enfamil Newborn is composed of:

      • Palm olein oil (44% of total fat), which provides high levels of palmitic and oleic acids. These fatty acids are predominant in human milk.
      • Soy oil (19.5% of total fat), which is a good source of the essential fatty acids linoleic and alpha-linolenic acid. These fatty acids are used to form DHA and ARA, which are important for visual and mental development.
      • Coconut oil (19.5% of total fat), which provides medium-chain saturated fatty acids. These saturated fats are easily digested, absorbed and utilized as a source of energy.
      • High-oleic sunflower oil (14.5% of total fat), which provides oleic acid. Oleic acid is an important source of energy for the infant and a component of nerve cell membranes, which are primarily formed in the first two years after birth.
      • A blend of DHA and ARA from single-cell oils (2.5% of total fat). This blend results in 0.32% of total fatty acids as DHA and 0.64% of total fatty acids as ARA.

      The levels of total fat and saturated, monounsaturated and polyunsaturated fatty acids in Enfamil Newborn are patterned after levels found in mature U.S. breast milk. Human milk contains, on average, between 20% and 24% of the fatty acids as palmitic acid. Using palm olein oil in the fat blend results in Enfamil Newborn having palmitic acid levels similar to breast milk. Linoleic acid provides about 17% of the total fatty acids in Enfamil Newborn, which is within the range of means found in average, mature U.S. breast milk (14%–19%).

      Newborn Fatty Acid Profile

      †† Pooled mean value across 9 studies of mature human milk in the U.S. ‡‡ Similac and Advance are registered trademarks of an entity unrelated to Mead Johnson & Company, LLC.

      DHA and ARA

      Enfamil formulas have our blend of DHA and ARA, two nutrients also found in breast milk that support brain and eye development and the immune system.

      Enfamil PREMIUM Infant DHA Level within Recommended Levels

      Carbohydrate

      The carbohydrate content in Enfamil Newborn is 43.5% of total Calories. The primary carbohydrate is lactose, which is the primary carbohydrate found in breast milk§§. The source of lactose in Enfamil Newborn is cow's milk. Enfamil Newborn also contains the prebiotic carbohydrates galactooligosaccharide (GOS) and polydextrose (PDX). GOS is synthesized from lactose and consists of short, variable-length chains of galactose ending in glucose, while PDX consists of random, highly branched glucose polymers plus sorbitol15,16. A prebiotic is defined as "a selectively fermented ingredient that allows specific changes, both in the composition and/or activity in the gastrointestinal microflora that confers benefits upon host well-being and health." Prebiotics like GOS and PDX are added to infant formula to substitute for some of the functional properties of human milk oligosaccharides (HMO) which, after lactose and lipid, is the third most abundant and complex component in human milk.

      Approximately 200 individual HMO structures have been identified and many are readily fermented by bifidobacteria, beneficial bacteria that typically reside in the infant gastrointestinal tract. In addition to stimulating the growth of beneficial bacteria, HMO have been shown to support mucosal immune function by interfering with the adhesion of a variety of pathogens to epithelial cells. The supplementation of infant formula with GOS and PDX, or prebiotic blends containing GOS and PDX, is designed to help achieve similar functional roles attributed to HMO.

      §§ Comparison based on carbohydrate content of average mature breast milk: remainder composed of oligosaccharides.

      Protein

      Enfamil Newborn provides 8.5% of Calories as protein, derived from whey and nonfat milk. (For comparison, human milk provides 6–7% of Calories as protein.) This protein level meets the growing infant's need for protein.

      Enfamil Newborn provides an easy-to-digest, 80:20 whey-to-casein protein blend patterned after typical early breast milk of days 3 through 5 of lactation16. With appropriate levels of essential and nonessential amino acids, the protein is of excellent quality and supports healthy growth and development.

      Vitamins and Minerals

      Enfamil Newborn provides vitamins and minerals at levels that meet the requirements of the Infant Formula Act and recommendations of the Life Sciences Research Organization (LSRO). These vitamin and mineral levels are appropriate to support infant growth and development.

      Calcium and Phosphorus

      Enfamil Newborn supplies 500 mg calcium and 280 mg phosphorus per quart, the same levels as in Enfamil Infant. This level of calcium is adequate to support bone mineralization in infants. The calcium to phosphorus ratio is 1.81:1, which is comparable to the ratio in human milk (2:1). A balanced level of calcium and phosphorus is important for adequate mineral utilization. Feeding Enfamil® for the first 4 months of life was shown to result in bone mineral content and bone mineral density comparable to that of breastfed infants at 4 years of age (before the addition of prebiotics) 14.

      Bioavalability of calcium from human milk is greater than that from infant formulas

      Iron

      Enfamil Newborn provides 11.5 mg iron per quart, the same level as in other Mead Johnson infant formulas. This level meets current recommendations for iron content of infant formulas. The American Academy of Pediatrics recommends that all infants who are not breastfed receive an iron-fortified formula19.

      Nucleotides

      Enfamil Newborn formula is patterned after average free nucleotide levels in breast milk—the gold standard.

      Nucleotides in breast milk versus Enfamil PREMIUM Newborn

      Higher levels of nucleotides are not associated with better outcomes.

      • Two expert panels concluded that there is not sufficient evidence to support additional benefits of adding nucleotides at higher levels than those recommended for infant formulas23,24,§§
      • The FDA and AAP have not established a recommended level for addition of nucleotides to infant formula
      • No dose response relationship between nucleotide levels in infant formulas and clinical outcomes in infants has been demonstrated23

      Recent expert panels found insufficient data to support additional benefits of increasing nucleotide intake to levels >5 mg/100 Calories

      The IEB did not find sufficient data to support additional benefits from increasing the intake of nucleotides to levels greater than 5mg/100 kcal

      §§ Recommend maximum of 5 mg total added nucleotides/100 Calories from the European Commission Scientific Committee on Food (SCF) and the ESPGHAN (European Society for Pediatric Gastroenterology, Hepatology and Nutrition) Coordinated International Expert Group (IEG)24,25.

      Enfamil Newborn also contains nucleotides at a level of 28 mg/L, similar to the average free nucleotide levels in human milk. Nucleotides are the building blocks of the genetic material RNA and DNA, which are integral to cell function and replication.

      Electrolytes—Sodium, Potassium and Chloride

      The electrolyte levels in Enfamil Newborn are within the ranges specified by U.S. Food and Drug Administration regulations, as mandated by the U.S. Infant Formula Act26. The sodium, potassium and chloride levels are 27 mg/100 Calories, 108 mg/100 Calories and 63 mg/100 Calories, respectively.

  • References
    • 1. Colombo J, Carlson SE, Cheatham CL, et al. Long-term effects of LCPUFA supplementation on childhood cognitive outcomes. Am J Clin Nutr. 2013;98:403-412.

      1. Scalabrin D, Mitmesser SH, Welling GW, et al. New prebiotic blend of polydextrose and galacto-oligosaccharides has a bifidogenic effect in young infants. J Pediatr Gastroenterol Nutr. 2012;54:343-352.

      3. Ziegler E, Vanderhoof JA, Petschow B, et al. Term infants fed formula supplemented with selected blends of prebiotics grow normally and have soft stools similar to those reported for breast-fed infants. J Pediatr Gastroenterol Nutr. 2007; 44:359-364.

      4. Nakamura N, Gaskins HR, Collier CT, et al. Molecular ecological analysis of fecal bacterial populations from term infants fed formula supplemented with selected blends of prebiotics. Appl Environ Microbiol. 2009; 75:1121-1128.

      5. Brenna JT, Varamini B, Jensen RG, et al. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr. 2007;85:1457-1464.

      6. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy. J Pediatr. 1999;134:11-14.

      7. Birch EE, Hoffman DR, Uauy R, et al. Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr Res. 1998;44:201-209.

      8. Koletzko B, Thiel I, Abiodun PO. The fatty acid composition of human milk in Europe and Africa. J Pediatr. 1992; 120(suppl):S62-S70.

      9. Data on file, Mead Johnson Nutritionals, September 2002.

      10. The British Nutrition Foundation. Recommendations for intakes of unsaturated fatty acids. In: Unsaturated Fatty Acids: Nutritional and physiological significance: The Report of the British Nutrition Foundation's Task Force. London: Chapman & Hall; 1992:152-163.

      11. FAO/WHO Joint Expert Consultation. Lipids in early development. In: Fats and oils in human nutrition. Report of a joint expert consultation. Food and Agriculture Organization of the United Nations and the World Health Organization. FAO Food and Nutr Pap. 1994;57:49-55.

      12. Simopoulos AP, Leaf A, Salem N Jr. Workshop on the essentiality and recommended dietary intakes for omega-6 and omega-3 fatty acids. J Am Coll Nutr. 1999;18:487-489.

      13. Koletzko B, Agostoni C, Carlson SE, et al. Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development. Acta Paediatr. 2001;90:460-464.

      14. Young RJ, Antonson DL, Ferguson PW, et al. Neonatal and infant feeding: effect on bone density at 4 years. J Pediatr Gastroenterol Nutr. 2005;41:88-93.

      15. Kunz C, Rudloff S, Baier W, et al. Oligosaccharides in human milk: structural, functional, and metabolic aspects. Annu Rev Nutr. 2000;20:699-722.

      16. Craig JF, Holden JP, Auerbach MH, Frier HI. Polydextrose as soluble fiber: physiological and analytical aspects. American Association of Cereal Chemists. 1998;43:370-376.

      17. Kunz C, Lönnerdal B. Re-evaluation of the whey protein/casein ratio of human milk. Acta Paediatr. 1992;81:107-112.

      18. American Academy of Pediatrics, Committee on Nutrition. Optimizing bone health and calcium intakes of infants, children, and adolescents. Pediatrics. 2006;117:578-585.

      19. American Academy of Pediatrics, Committee on Nutrition. Iron fortification of infant formulas. Pediatrics. 1999;104:119-123.

      20. Sugawara M, Sato N, Nakano T, et al. Profile of nucleotides and nucleosides of human milk. J Nutr Sci Vitaminol (Tokyo). 1995;41:409-418.

      21. Leach JL, Baxter JH, Molitor BE, et al. Total potentially available nucleosides of human milk by stage of lactation. Am J Clin Nutr. 1995;61:1224-1230.

      22. Data on file, Mead Johnson Nutrition. March 1998.

      23. European Commission Scientific Committee on Food. Report of the Scientific Committee on Food on the Revision of Essential Requirements of Infant Formulae and Follow-on Formulae. Brussels, Belgium; 2003.

      24. Koletzko B, Baker S, Cleghorn G, et al. Global standard for the composition of infant formula: recommendations of an ESPGHAN coordinated international expert group. J Pediatr Gastroenterol Nutr. 2005;41:584-599.

      25. Nutrient Requirements for Infant Formulas. Code of Federal Regulations 21, C.F.R. 107.100. April 1, 2006.

  • Retail Availability
    • Available at these and other fine stores:
      Wal-Mart Fred Meyer Wakefern
      Kroger Publix Wegman's
      Albertsons Walgreen's A & P
      Safeway Bashas Markets Schnucks
      HEB CVS Vons
      Target Rite Aid Dominick's
      K-Mart Meijer Ralph's
      Bruno's Giant Foods Toys 'R Us
      Winn Dixie Marsh Babies 'R Us
      Food Lion

      Availability varies depending on the size of the store, as all stores do not carry all of these products. Typically, the larger the store, the more likely it is that these products will be available in the store you visit. If you find one of the stores listed above does not have the product you need, please ask the store manager to order the quantity you will need on a monthly basis.

      It is possible that a specific store in one of these chains may not accept Women, Infants and Children vouchers.

      For your convenience, you can go shop online or find a retail store in your area to purchase this product.

      If you have a question or want to purchase Ready to Use Nursette® bottles (Women, Infants and Children vouchers cannot be accepted for these purchases), you can call 1-800-BABY123.

      *No endorsement of any brand or product by the USDA is implied or intended.